Our drive north to Asheville, North Carolina will take us through the foothills of the Appalachian Mountains to the 8,000 acre estate built by George Vanderbilt. The Biltmore House, opened on Christmas Eve, 1895, is still the largest house in America. This French Renaissance chateau contains 250 rooms, complete with 65 fireplaces, 34 bedrooms, an indoor pool, a bowling alley and more.